Natural pomegranate and raspberry flavor. Sweetened with fructose and monoammonium glycyrrhizinate (from licorice). Two (2) tablets are equivalent to 1 capsule.
- Better breakdown of fruits and vegetables
- Helps support digestion of polyphenols (“phenols”)
- Tends to soften stools
- Capsules or chewable tablets
No-Fenol was developed by Dr. Devin Houston in response to requests for a product that would support the digestion of fruits and vegetables, without the problems thought to be associated with polyphenolic compounds. Responses from customers indicate that for many, No-Fenol does allow the addition of these foods to the diet without complications.
All plants contain some degree of polyphenolic compounds (sometimes called “phenols”). The polyphenol structure itself is found everywhere in nature, and is essential to many of life’s processes.
Current thinking by many is that some subset of children on the autism spectrum have difficulty in the processing of polyphenolic compounds, which may present as behavioral problems and physical symptoms such as red ears and cheeks, and dark circles under the eyes. While the basic mechanism behind this phenomenon is not well defined, it is thought that perhaps the polyphenolic compounds become “trapped” in some part of a metabolic cycle, presumbably involved with various detoxification pathways.
The research literature indicates that some polyphenolic compounds are modified by the addition of carbohydrate groups to their structures, which may inhibit their crossing into cells and being metabolized.
The current hypothesis for why No-Fenol may help is through the ability of the enzymes in this product to remove the carbohydrate groups from the polyphenols, thus allowing normal processing by the detoxification pathways.
There is no evidence that No-Fenol directly modifies polyphenolic structures. Indeed, the success of No-Fenol in allowing the addition of polyphenolic foods back into the diet of children with autism may result in a re-evaluation of the basis of the polyphenol “problem”.
Xylanase is the major component of No-Fenol, and is an enzyme used to breakdown the structural components of plant cell walls, which are primarily very complex carbohydrates. Xylanase is used in the juice industry to extract more juice from fruit pulp fibers.
At least one reference indicates that polyphenolic compounds are actually increased by treatment with xylanase. Based on this reference and the fact that No-Fenol has allowed “phenol-sensitive” individuals to ingest polyphenolic foods, Houston Enzymes now believes that the polyphenol issue is much more complex than previously thought, and may not be due so much to the presence of phenols as to the specific structure of these polyphenols.
No-Fenol capsules contains cellulose/medium-chain triglyceride oil (MCT oil) as filler. MCT oil is derived from palm oil, and the cellulose is derived from European Spruce trees. The capsule is also cellulose.
Contraindications for Enzyme Supplementation
This product may not be appropriate for those with known allergies to enzyme proteins, though non-specific mold allergies do not necessarily preclude use of fungal enzymes. Consult your medical doctor for further advice, and err on the side of caution. Those with known anaphylactic allergic reactions to fungal proteins should NOT ingest fungal-derived enzymes.
Serving Size: 2 Tablet
Servings per Container: 90
|Amount Per Serving||% Daily Value|
|Enzyme Blend Weight||317 mg||*|
|CereCalasetm (1500 MU) Hemicellulase, beta-glucanase, phytase||83 mg||*|
|*Daily Value Not Established|
|Other Ingredients: Fructose, natural pomegranate flavor, hydroxypropyl cellulose, natural raspberry flavor, magnesium stearate, citric acid, silica, monoammonium glycyrrhizinat (flavor enhancer from licorice), sodium chloride. No added starch, dairy, yeast, wheat, gluten, corn, soy, nuts, preservatives, artificial colors, artificial flavors or animal derivatives.|
As a dietary supplement, chew 1 – 2 tablets with meals or snacks. Dosing is not by age or body weight, but by how much food is eaten. Note that it now takes 2 chewable tablets to equal the potency of 1 No-Fenol capsule.
Store in a cool, dry place away from direct light and humid conditions. Do not refrigerate, keep at room temperature. Cold does not harm the enzymes, but most refrigerators are high-humidity environments. Freezing is acceptable and encouraged for long-term storage.